Drybench Virtual Wet Lab.

Follow a liquid-transfer plan through a three-dimensional bench. Inspect each well's nominal volume, concentration and material origins; change an action and compare the result with the original. Open your own supported plan, or bring a prepared serial-dilution recipe from the calculators.

For each transfer, the model subtracts the withdrawn volume and proportional material amounts from a declared homogeneous source, then adds them to the destination. Every channel is checked before any part of a multichannel action changes the state. Unknown composition remains unknown. Mixing is a declaration made by the plan, not a fluid-dynamics prediction.

The original and edited preparations are retained separately. Save a private protocol in your research workspace or download its versioned project file. Reopening preserves the declared setup and synthetic-example status. The animation illustrates the same accepted states that appear in the table.

Material balance for an ideal homogeneous transfer: Δn = n_source × ΔV / V_source; C = n / V when V > 0. Exact rational reference: pipeline/virtual-wet-lab/reference.py, reference 1.0.0.

A transfer checks every source, destination, instrument and channel before updating any container. If a check fails, the previous accepted state remains. An empty destination inherits a homogeneous aliquot; adding to a nonempty destination records it as unmixed, and aspiration then waits for an explicit declaration of homogeneity. Known amounts follow the withdrawn fraction; unknown amounts remain unknown. Empty wells have no concentration.

Material history reports nominal source ancestry. Possible contact through reused tips is a separate graph, without a probability or contamination amount. No residual liquid is assigned by default.

Save a private protocol to the research workspace, download a versioned project JSON file, or export a transfer list. The original and working plans, setup assumptions, model version and synthetic-example status stay attached. A project is a preparation plan, not evidence that work was performed.

Supported own-plan JSON uses schema virtual-wet-lab.plan, version 1. It declares materials, labware, containers, instruments and ordered transfer or mix commands. Volumes are litres and material amounts are moles. Every material amount must be supplied explicitly as a non-negative number or null for unknown. Unsupported versions or malformed input are refused without replacing the current plan.

For a prepared 96-well serial dilution in the calculators, Experimental opens a local setup handoff. Tube preparation and plate dispensing retain the calculator's sequence. Declare source inventories, capacities, reserves and instrument limits before accepting the preparation. A preparation allowance is not a withdrawal reserve and is not charged twice.

pipeline/virtual-wet-lab/reference.py

Separately implemented exact rational SI reference and refusal cases, committed before production arithmetic.

src/lib/wet-lab/engine.test.ts

All applicable reference cases, conservation, explicit unknowns, atomic multichannel refusal and comparison.

src/lib/wet-lab/calc-import.test.ts

Native Calc preparation and control semantics, source consistency and refusal of unsupported inputs.

src/apps/virtual-wet-lab/worker/client.test.ts

Worker cancellation, stale-response fencing and bounded startup/computation.

The reference was committed before the production arithmetic. It uses Python Fraction for exact rational SI amounts, volumes and origins, plus hand-specified atomic refusal cases. Sixteen scenarios apply to the first transfer/mix model. A seventeenth records a future partial-tip primitive which this version does not support.

These are numerical reference checks on a stated ideal model. They do not measure a pipette, establish effective mixing or predict a biological outcome.

The app contacts no host but its own.