{
 "about": {
  "what": "(c) The reduction: the 33 scenarios of Bioreactor verification 0.2.0 with the specification's allocation at the product's defaults (Yps = Yxs, MPc = MXc, γP = γX), against 0.2.0 as published",
  "source": {
   "scenarios": "public/verification/bioreactor-simulator/0.2.0/scenarios.json",
   "sha256": "614bce70c89ce2cb0c527f2ba2b7345e7f13190111e7a87acf713ebb2c465103",
   "scriptSha256": "2ffcb6742759cf7c03da8b83272baf8601fa8bfea12efded47f1634852453fcb",
   "scenarios_count": 33
  },
  "solver": {
   "path": "pipeline/bioreactor-simulator/reference.py",
   "sha256": "6e1f493108e750856ef676935ee11d290efc5cfade88daf2e3af5e997268baa4",
   "note": "loaded by path and unchanged; differs from 0.2.0's script (2ffcb674…, commit 732ac1258) only in its docstring and in carrying feedDO and flow through aeration_at, which no 0.2.0 scenario sets"
  },
  "control": "reference.py's solve as it stands, on each scenario's inputs: must reproduce 0.2.0's every result as written (byte-identical JSON) before the substitution is run",
  "substitution": "derived (adds Yps, MPc, γP and the product's carbon mass fraction, at their defaults), switches (Yps·(qS − ms) − β), rates_in and demand_rates (the allocation and the gas balances with the product's own carbon and electrons), design_rate ([μ/Yxs + (αμ + β)/Yps + ms]·X·V/(Sf − S)) and Run.rhs (washout with the product's own carbon and electrons); solve, the events, the oxygen side, the triggers and the output grid unchanged",
  "tiers": {
   "gate": {
    "outputFractionOfPeak": 0.005,
    "eventHours": 0.001,
    "closure": 0.005
   },
   "tight": {
    "outputFractionOfPeak": 1e-09,
    "eventHours": 1e-08
   },
   "rule": "gate (T3-gate, decides the version): output times, regime sequences, switch counts and trigger counts equal; every output within the fraction of its 0.2.0 peak; switch, event, trigger and segment times within the hours; resolved feeds within the same fraction; closures within 0.5 percent. tight (T3-tight, reported, not a gate): the same with the tight values, against the control, which equals 0.2.0 as written (so the comparison with the published file is the comparison with the control); applied without the 12-significant-figure rounding allowance the CSO permits, so stricter than ruled. Any deviation above 1e-6 of peak is to be explained before it reaches the CEO"
  },
  "version": "0.15.0",
  "recordedOn": "2026-10-31",
  "script": "pipeline/bioreactor-simulator/reference-product-composition.py",
  "generatorSha256": "81421db2e2689f1562f85f8a17b17b14ad71cee17f2eaf981fa1acacc40930f9",
  "python": "3.12.14",
  "specification": "docs/design/bioreactor-product-composition.md",
  "ruling": [
   "docs/board/memos/2026-10-24-cso-bioreactor-stage.md",
   "docs/board/memos/2026-10-31-cso-bioreactor-br8-allocation.md"
  ]
 },
 "summary": {
  "scenarios": 33,
  "controlReproduced": 33,
  "withinGate": 33,
  "withinTight": 33,
  "identicalAsWritten": 0,
  "movedBeyondGate": [],
  "movedBeyondTight": [],
  "differFromPublishedBytes": [
   "batch-monod",
   "batch-monod-small-ks",
   "batch-product",
   "batch-haldane",
   "batch-starvation",
   "fed-batch-exponential",
   "fed-batch-exponential-small-ks",
   "fed-batch-exponential-capped",
   "fed-batch-exponential-methanol",
   "fed-batch-constant",
   "fed-batch-constant-overfeed",
   "fed-batch-constant-stop",
   "fed-batch-rescued",
   "chemostat-steady",
   "chemostat-step",
   "chemostat-washout",
   "oxygen-limited-kla-50-dynamic",
   "oxygen-limited-kla-50-qss",
   "oxygen-limited-kla-200-dynamic",
   "oxygen-limited-kla-200-qss",
   "oxygen-limited-kla-1000-dynamic",
   "oxygen-limited-kla-1000-qss",
   "oxygen-step-kla-20-40-dynamic",
   "oxygen-step-kla-20-40-qss",
   "planted-excursion-06",
   "planted-excursion-04",
   "preset-e-coli-fed-batch@1",
   "preset-e-coli-fed-batch@1-rescued",
   "preset-s-cerevisiae-fed-batch@1",
   "preset-s-cerevisiae-fed-batch@1-chemostat",
   "preset-pichia-aox1@1",
   "preset-chemostat@1",
   "preset-custom@1"
  ],
  "worstOutputFractionOfPeak": 6.78e-10,
  "worstSwitchHours": 0.0,
  "anyDefaultCurveMoves": false
 },
 "scenarios": [
  {
   "id": "batch-monod",
   "mode": "batch",
   "hasProduct": false,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 0.0,
    "S": 2.7e-16,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 5.69e-19,
    "OTR": 3.97e-14,
    "CER": 5.48e-19,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 3.97e-14,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 0.0,
    "P": 0.0,
    "V": 0.0,
    "DO": 1.21e-12,
    "Cstar": 1.08e-11,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 2.59e-15,
    "OTR": 9.07e-12,
    "CER": 2.5e-15,
    "yO2out": 1.08e-11
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 1.46e-16,
    "electronClosure": 8.79e-16
   },
   "closure": {
    "carbonClosure": 8.777e-16,
    "electronClosure": 2.195e-16
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "batch-monod-small-ks",
   "mode": "batch",
   "hasProduct": false,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 0.0,
    "S": 2.68e-19,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 1.41e-15,
    "CER": 0.0,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 1.41e-15,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 0.0,
    "P": 0.0,
    "V": 0.0,
    "DO": 4.83e-14,
    "Cstar": 0.0,
    "mu": 1.98e-08,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 0.0,
    "CER": 0.0,
    "yO2out": 0.0
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 1.46e-16,
    "electronClosure": 2.2e-16
   },
   "closure": {
    "carbonClosure": 4.389e-16,
    "electronClosure": 2.195e-16
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "batch-product",
   "mode": "batch",
   "hasProduct": true,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 0.0,
    "S": 9.26e-16,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 8.49e-14,
    "CER": 0.0,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 8.49e-14,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 0.0,
    "P": 0.0,
    "V": 0.0,
    "DO": 1.32e-11,
    "Cstar": 0.0,
    "mu": 9.28e-10,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 0.0,
    "CER": 0.0,
    "yO2out": 0.0
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 2.95e-16,
    "electronClosure": 2.22e-16
   },
   "closure": {
    "carbonClosure": 0.0,
    "electronClosure": 4.431e-16
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "batch-haldane",
   "mode": "batch",
   "hasProduct": true,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 0.0,
    "S": 1.67e-15,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 1.39e-13,
    "F": 0.0,
    "OUR": 6.5e-14,
    "OTR": 6.5e-13,
    "CER": 1.69e-14,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 6.5e-13,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 2.19e-15,
    "P": 0.0,
    "V": 0.0,
    "DO": 4.51e-14,
    "Cstar": 2.15e-11,
    "mu": 4.08e-10,
    "F": 0.0,
    "OUR": 3.19e-12,
    "OTR": 1.53e-10,
    "CER": 6.07e-13,
    "yO2out": 4.77e-10
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 6.65e-16,
    "electronClosure": 1.17e-15
   },
   "closure": {
    "carbonClosure": 2.216e-16,
    "electronClosure": 1.169e-16
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "batch-starvation",
   "mode": "batch",
   "hasProduct": false,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 0.0,
    "S": 4.01e-15,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 6.8e-20,
    "OTR": 6.14e-14,
    "CER": 6.58e-20,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 6.14e-14,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 0.0,
    "P": 0.0,
    "V": 0.0,
    "DO": 6.97e-14,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 0.0,
    "CER": 0.0,
    "yO2out": 0.0
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 6.97e-16,
    "electronClosure": 5.15e-16
   },
   "closure": {
    "carbonClosure": 6.972e-16,
    "electronClosure": 8.588e-16
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "fed-batch-exponential",
   "mode": "fed-batch",
   "hasProduct": false,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 3.02e-13,
    "S": 3.41e-16,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 3.8e-14,
    "OTR": 7.59e-15,
    "CER": 3.68e-14,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 3.02e-13,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 1.96e-18,
    "P": 0.0,
    "V": 0.0,
    "DO": 5.01e-13,
    "Cstar": 0.0,
    "mu": 6.02e-12,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 0.0,
    "CER": 0.0,
    "yO2out": 0.0
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 6.41e-16,
    "electronClosure": 0.0
   },
   "closure": {
    "carbonClosure": 5.552e-15,
    "electronClosure": 5.129e-15
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "fed-batch-exponential-small-ks",
   "mode": "fed-batch",
   "hasProduct": false,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 0.0,
    "S": 1e-17,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 3.79e-12,
    "OTR": 3.16e-16,
    "CER": 3.67e-13,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 3.79e-12,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 1.68e-12,
    "P": 0.0,
    "V": 0.0,
    "DO": 3.59e-15,
    "Cstar": 7.11e-12,
    "mu": 2.94e-07,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 0.0,
    "CER": 0.0,
    "yO2out": 0.0
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 0.0,
    "electronClosure": 7e-16
   },
   "closure": {
    "carbonClosure": 1.584e-13,
    "electronClosure": 1.508e-13
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "fed-batch-exponential-capped",
   "mode": "fed-batch",
   "hasProduct": true,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 2.8e-14,
    "S": 0.0,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 0.0,
    "CER": 0.0,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 2.8e-14,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 0.0,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 0.0,
    "OTR": 0.0,
    "CER": 0.0,
    "yO2out": 8.47e-10
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 1.24e-15,
    "electronClosure": 1.49e-15
   },
   "closure": {
    "carbonClosure": 7.576e-15,
    "electronClosure": 7.83e-15
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "fed-batch-exponential-methanol",
   "mode": "fed-batch",
   "hasProduct": true,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 3.82e-11,
    "S": 5.17e-10,
    "P": 5.09e-11,
    "V": 2.32e-11,
    "DO": 2.43e-10,
    "Cstar": 1.07e-10,
    "mu": 4.36e-10,
    "F": 0.0,
    "OUR": 2.23e-10,
    "OTR": 2.72e-10,
    "CER": 2.08e-10,
    "yO2out": 1.06e-10,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 5.17e-10,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 1.72e-08,
    "P": 0.0,
    "V": 0.0,
    "DO": 1.09e-09,
    "Cstar": 9.2e-11,
    "mu": 8.59e-08,
    "F": 0.0,
    "OUR": 4.26e-08,
    "OTR": 7.71e-11,
    "CER": 8.09e-08,
    "yO2out": 3.63e-10
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 0.0,
    "electronClosure": 2e-16
   },
   "closure": {
    "carbonClosure": 2.699e-15,
    "electronClosure": 4.398e-15
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "fed-batch-constant",
   "mode": "fed-batch",
   "hasProduct": false,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 0.0,
    "S": 1e-15,
    "P": 0.0,
    "V": 0.0,
    "DO": 0.0,
    "Cstar": 0.0,
    "mu": 1.67e-13,
    "F": 0.0,
    "OUR": 3.5e-18,
    "OTR": 1.99e-14,
    "CER": 9.82e-13,
    "yO2out": 0.0,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 9.82e-13,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 1.96e-18,
    "P": 0.0,
    "V": 0.0,
    "DO": 2.71e-13,
    "Cstar": 7.97e-11,
    "mu": 0.0,
    "F": 0.0,
    "OUR": 4.89e-12,
    "OTR": 1.06e-10,
    "CER": 0.0,
    "yO2out": 2.56e-12
   },
   "switchHours": 0.0,
   "eventHours": 0.0,
   "triggerHours": {
    "oxygen": 0.0,
    "respiratory": 0.0,
    "overflow": 0.0
   },
   "segmentHours": 0.0,
   "resolvedFeedRelative": 0.0,
   "closureDifference": {
    "carbonClosure": 2.06e-16,
    "electronClosure": 3.08e-16
   },
   "closure": {
    "carbonClosure": 6.172e-16,
    "electronClosure": 1.235e-15
   },
   "withinGate": true,
   "withinTight": true
  },
  {
   "id": "fed-batch-constant-overfeed",
   "mode": "fed-batch",
   "hasProduct": true,
   "controlIdenticalAsWritten": true,
   "identicalAsWritten": false,
   "outputTimesEqual": true,
   "regimeSequenceEqual": true,
   "outputsFractionOfPeak": {
    "X": 1.18e-11,
    "S": 3.67e-10,
    "P": 3.16e-11,
    "V": 0.0,
    "DO": 1.22e-10,
    "Cstar": 6.32e-11,
    "mu": 3.86e-10,
    "F": 0.0,
    "OUR": 6.28e-10,
    "OTR": 6.78e-10,
    "CER": 5.97e-10,
    "yO2out": 6.71e-11,
    "kLa": 0.0
   },
   "worstOutputFractionOfPeak": 6.78e-10,
   "slopesFractionOfPeak": {
    "X": 0.0,
    "S": 1.54e-08,
    "P": 0.0,
    "V": 0.0,
    "DO": 8.73e-10,
    "Cstar": 3.61e-11,
    "mu": 3.47e-07,
    "F": 0.0,
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}
